2022 GMC Sierra 2500HD Fuse Box Diagram & Amperage

As an ASE-certified master technician, I know firsthand that electrical gremlins can bring a heavy-duty workhorse like the 2022 GMC Sierra 2500HD to a grinding halt. Whether your trailer brakes suddenly stopped responding, your infotainment screen went black, or your 12V accessory port isn't charging your tools, the first place to check is always the fuse box.

This comprehensive guide covers the fuse box diagrams, amperage ratings, and locations for the 2022 GMC Sierra 2500HD. Please note that exact fuse configurations can vary based on your specific engine (gas vs. Duramax diesel) and trim level (Pro, SLE, SLT, AT4, Denali). Always verify against the printed legend on the inside of your fuse box lid.

Quick Answer: Fuse Box Locations

The 2022 GMC Sierra 2500HD features three primary fuse blocks to manage its extensive electrical and towing systems:

1. Engine Compartment Fuse Block: Located on the passenger side of the engine bay, near the battery.
2. Left Instrument Panel Fuse Block: Located on the driver's side of the dashboard, behind a removable cover on the edge of the instrument panel (visible when the door is open).
3. Right Instrument Panel Fuse Block: Located on the passenger side of the dashboard, accessed similarly by removing the side cover panel.

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Engine Compartment Fuse Block

The under-hood fuse block handles high-draw systems, powertrain controls, heavy-duty cooling, and most of your critical trailer electrical circuits.

Relays are also located in this box for the Starter, A/C Clutch, Fuel Pump, and Trailer Backup circuits.

Fuse #	Amp	Color	Circuit / Component Protected
11	20A	Yellow	Trailer Reverse Lamps / Backup
15	10A	Red	A/C Clutch
21	30A	Pink	ABS Pump
24	30A	Pink	Trailer Brakes (Integrated Trailer Brake Controller)
26	30A	Pink	Starter Motor / Starter Relay
35	15A	Blue	Engine Control Module (ECM) / Powertrain Control Module (PCM)
42	20A	Yellow	Fuel Pump
45	10A	Red	Headlights - High Beam (Left)
46	10A	Red	Headlights - High Beam (Right)
52	10A	Red	Ignition System / Ignition Coils
68	30A	Pink	Cooling Fan / Blower Motor (Under-hood)
74	30A	Pink	Trailer Power (12V Auxiliary)
78	15A	Blue	Headlights - Low Beam (Right)
79	15A	Blue	Headlights - Low Beam (Left)
82	20A	Yellow	Trailer Stop/Turn (Right)
83	20A	Yellow	Trailer Stop/Turn (Left)
87	10A	Red	Engine Control Module (Ignition)
91	15A	Blue	Horn

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Left Instrument Panel Fuse Block

The left dash fuse box primarily protects driver-centric controls, interior lighting, and critical safety restraints.

Fuse #	Amp	Color	Circuit / Component Protected
F4	15A	Blue	Body Control Module (BCM) 1
F11	10A	Red	Sensing and Diagnostic Module (Airbags)
F17	15A	Blue	Steering Wheel Controls
F22	15A	Blue	Heated Seats / Steering Wheel
F27	10A	Red	Instrument Cluster / Dashboard Display
F31	15A	Blue	Body Control Module (BCM) 2
F38	20A	Yellow	Power Windows (Driver side)
F44	10A	Red	Ignition / Push Button Start
F49	10A	Red	Data Link Connector (OBD-II Port)
F52	30A	Pink	Blower Motor (HVAC Cabin Blower)

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Right Instrument Panel Fuse Block

The right dash fuse block manages infotainment, passenger-side accessories, and various cabin power outlets.

Fuse #	Amp	Color	Circuit / Component Protected
F3	15A	Blue	Radio / Infotainment System
F9	20A	Yellow	Cigar Lighter / 12V Auxiliary Power Outlet (Front)
F14	10A	Red	USB Ports / Media Hub
F16	20A	Yellow	12V Auxiliary Power Outlet (Rear)
F24	15A	Blue	Amplifier (Premium Audio)
F32	10A	Red	Passenger Sensing System (Airbag)
F41	20A	Yellow	Power Windows (Passenger side)
F48	15A	Blue	Sunroof (if equipped)
F51	20A	Yellow	Trailer Camera System

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How to Test a Fuse

As a master technician, I always recommend testing fuses rather than just relying on a visual inspection. Sometimes a fuse can suffer a hairline fracture that is invisible to the naked eye but still breaks the circuit.

Method 1: Visual Inspection

1. Ensure the ignition is OFF.
2. Use the fuse puller tool (usually located inside the engine compartment fuse block lid) or needle-nose pliers to pull the suspected fuse.
3. Hold it up to the light. Look at the U-shaped wire inside. If it is broken, melted, or blackened, the fuse is blown and must be replaced.

Method 2: Multimeter Test (The Pro Way)

1. Set your digital multimeter to the continuity setting (the one that beeps) or Ohms (resistance).
2. You don’t even need to remove the fuse for this. Modern blade fuses have two small metal testing tabs on the top.
3. Touch one multimeter probe to each tab.
4. If the multimeter beeps (or reads near 0 ohms), the fuse is good. If there is no beep (or it reads OL/Open), the fuse is blown.

Pro Tip: Never replace a blown fuse with one of a higher amperage rating. Doing so can cause wires to melt and potentially start an electrical fire.

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Common Blown Fuses on this Vehicle

Heavy-duty trucks like the 2022 Sierra 2500HD are often used for demanding tasks, which can put stress on certain electrical circuits. Here is what I see blown most often in the shop:

1. Trailer Lighting & Power Fuses (Under-hood #11, #74, #82, #83) Why it blows: Towing different trailers means dealing with different wiring conditions. A short circuit in a rusty trailer harness or a poorly wired aftermarket trailer accessory is the #1 cause of blown trailer fuses. What to check: Before replacing the fuse, inspect the 7-way plug on your bumper and the wiring harness on the trailer for chafing, water intrusion, or bent pins.

2. 12V Power Outlets / Cigar Lighter (Right Dash #F9, #F16) Why it blows: Dropping a penny into the 12V socket, or plugging in a high-draw accessory like a heavy-duty tire inflator or a faulty power inverter. What to check: Look inside the 12V socket for debris or coins. Ensure the accessory you are plugging in does not exceed the 20-amp limit.

3. Radio / Infotainment (Right Dash #F3) Why it blows: Over-the-air software updates crashing the system, or shorted USB cables plugged into the media hub. What to check: If your screen goes black, check this fuse. Often, just pulling the fuse for 60 seconds and putting it back in (a hard reset) will bring the infotainment system back to life without the fuse actually being blown.

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