2021 GMC Sierra 2500HD Fuse Box Diagram & Amperage
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Quick answer
The 2021 GMC Sierra 2500HD has three main fuse box locations: under the hood (engine compartment), inside the cabin (driver's side dash kick panel), and in the rear (under the rear seat on the driver's side).
Having issues with your 2021 GMC Sierra 2500HD's electrical system? A blown fuse could be the culprit! This guide provides a comprehensive overview of the fuse box locations, diagrams, amperage ratings, and the circuits they protect. Remember to always consult your vehicle's owner's manual and the fuse box lid for the most accurate and up-to-date information, as fuse configurations can vary slightly due to trim levels and options.
Under-Hood Fuse Box
The under-hood fuse box is located in the engine compartment, typically on the driver's side near the battery. It contains fuses and relays for critical engine functions, powertrain control, major electrical systems, and trailer connections.
| Fuse # | Amp | Color | Circuit / Component Protected |
|---|---|---|---|
| F1 | 60A | Yellow | Main Power (Ignition 1) |
| F2 | 60A | Yellow | Main Power (Ignition 2) |
| F3 | 50A | Red | ABS Pump Motor |
| F4 | 40A | Green | Trailer Brake Control |
| F5 | 30A | Green | Blower Motor |
| F6 | 30A | Green | ECM/PCM (Powertrain Control Module) |
| F7 | 25A | Natural | Fuel Pump |
| F8 | 20A | Yellow | Headlights (Low Beam - Left) |
| F9 | 20A | Yellow | Headlights (Low Beam - Right) |
| F10 | 15A | Blue | Ignition Coils |
| F11 | 15A | Blue | Starter Relay |
| F12 | 10A | Red | A/C Compressor Clutch |
| F13 | 10A Red | Tail Lights (Left) | |
| F14 | 10A Red | Tail Lights (Right) | |
| F15 | 20A Yellow | BCM (Body Control Module) Supply | |
| F16 | 25A Natural | Trailer Power (Constant) | |
| F17 | 30A Green | Power Mirror / Power Window |
Relay Locations (Under-Hood):
- RL1 (Starter Relay): Controls power to the starter motor.
- RL2 (Fuel Pump Relay): Powers the fuel pump.
- RL3 (Ignition Relay): Supplies power to the ignition system.
- RL4 (Headlight Relay): Controls headlight operation.
- RL5 (Blower Motor Relay): Powers the blower motor for HVAC.
- RL6 (A/C Clutch Relay): Engages and disengages the A/C compressor clutch.
- RL7 (Trailer Brake Relay): Provides power for the trailer brake controller.
Cabin Fuse Box (Instrument Panel Fuse Block)
The cabin fuse box is located inside the vehicle on the driver's side, typically behind a removable panel on the side of the dashboard (the kick panel). This fuse box primarily handles interior electrical components, accessories, and convenience features.
| Fuse # | Amp | Color | Circuit / Component Protected |
|---|---|---|---|
| F1 | 25A | Natural | Blower Motor (HVAC System) |
| F2 | 20A | Yellow | Radio / Infotainment System |
| F3 | 15A | Blue | Accessory Power Outlet (Cigar Lighter) |
| F4 | 15A | Blue | USB Ports / Auxiliary Power |
| F5 | 10A | Red | Instrument Cluster |
| F6 | 10A | Red | ABS Module (Control) |
| F7 | 10A | Red | Airbag (SRS) System |
| F8 | 10A | Red | Brake Lights |
| F9 | 5A | Tan | ECM/PCM (Keep Alive Memory) |
| F10 | 5A | Tan | Ignition Switch |
| F11 | 15A | Blue | Power Windows |
| F12 | 15A | Blue | Power Door Locks |
| F13 | 10A | Red | Interior Lights / Dome Light |
| F14 | 5A | Tan | HVAC Control Head |
| F15 | 20A | Yellow | Trailer Brake Controller (Cabin) |
Rear Fuse Box
The rear fuse box in the 2021 GMC Sierra 2500HD is typically located under the rear seat on the driver's side. This fuse box often contains fuses for electrical components found in the rear of the vehicle, such as trailer connections, power outlets, and certain body control functions.
| Fuse # | Amp | Color | Circuit / Component Protected |
|---|---|---|---|
| F1 | 40A | Green | Trailer Auxiliary Power |
| F2 | 30A | Green | Power Inverter (If Equipped) |
| F3 | 20A | Yellow | Rear Accessory Power Outlet |
| F4 | 20A | Yellow | Rear Window Defogger |
| F5 | 15A | Blue | Trailer Stop/Turn Lights (Left) |
| F6 | 15A | Blue | Trailer Stop/Turn Lights (Right) |
| F7 | 10A | Red | Trailer Park/Tail Lights |
How to Test a Fuse
If you suspect a blown fuse, here's how to safely test it:
- Locate the Fuse Box: Refer to your owner's manual or the quick answer section above to find the correct fuse box.
- Identify the Suspect Fuse: Open the fuse box lid and consult the diagram on the lid or in your owner's manual to find the fuse for the problematic component.
- Carefully Remove the Fuse: Use a fuse puller (usually found within the fuse box or tool kit) to gently remove the suspect fuse. Never use metal tools that could short circuits.
- Inspect the Fuse: Hold the fuse up to a light and look for a broken wire inside the fuse. If the wire is broken or charred, the fuse is blown. For blade-type fuses, you can also look for discoloration.
- Use a Multimeter (Optional but Recommended): For a more definitive test, set your multimeter to the continuity setting. Touch one probe to each metal terminal of the fuse. A good fuse will show continuity (the multimeter will beep or display a reading close to zero ohms). A blown fuse will show no continuity.
- Replace with a New Fuse: If the fuse is blown, replace it with a new fuse of the exact same amperage rating and type. Never use a fuse with a higher amperage, as this can lead to serious electrical damage or fire.
Common Blown Fuses on This Vehicle
While any overcurrent situation can blow a fuse, some fuses are more commonly affected due to their circuits or components. Here are a few to check first if you're experiencing related issues:
- Cigar Lighter / 12V Outlets: These fuses (often F3 in the cabin fuse box) are frequently blown due to short circuits from chargers, air fresheners, or other accessories. If your phone isn't charging, this is a good place to start.
- Blower Motor: If your HVAC fan isn't working on any speed, check the blower motor fuse (F5 in the under-hood fuse box or F1 in the cabin fuse box, depending on the fault). A failing blower motor or a blockage can draw excessive current.
- Headlights: If one or both of your headlights are out, check their respective fuses (F8 and F9 in the under-hood fuse box). While bulbs are a more common failure, a short in the wiring can blow the fuse.
- Trailer Brake Control: For those who frequently tow, the trailer brake control fuse (F4 in the under-hood or F15 in the cabin) can blow if there's a short in the trailer's wiring or the brake controller itself. Always inspect your trailer's wiring before troubleshooting the truck.
Always verify the printed legend in the fuse box lid against your owner's manual, as certain trim levels or optional equipment may have slight variations in fuse assignments.
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Before you pull a fuse on the 2021 GMC Sierra 2500HD
- Use the label printed on the panel cover or the owner's manual for your exact build. Layouts change with options, model year and build date, so a chart for another truck can be wrong.
- Replace a blown fuse only with the same amp rating. A larger fuse can let wiring overheat.
- A fuse that blows again right away means a short or failing component downstream. Find the cause before replacing it again.
- A good fuse doesn't prove the circuit works — relays, grounds and connectors fail too.
- Disconnect the battery before working near high-current fuses or cables.
Learn more: How fuses, relays and truck electrical systems work
More specs for the 2021 GMC Sierra 2500HD
Oil Capacity & Filter
Capacity, weight, filter PN, drain plug torque, change interval.
Fluid Type Specs
Engine oil, coolant, ATF, diff, brake, PS, DEF — with OEM spec numbers.
Coolant Capacity & Type
Total system capacity, OEM coolant spec, flush interval, bleed tips.
Transmission Fluid & Service
Trans model, fluid spec, capacity, filter PN, service interval.
Torque Specifications
Lug nuts, drain plug, caliper, axle nut, plug, key fasteners.
Brake Pad & Rotor Specs
Pad PNs, rotor size, min thickness, caliper torque.
Tire Size & Pressure
OEM size, cold psi, bolt pattern, wheel size, TPMS.
Battery Size & Group
Group size, CCA, AGM/flooded, dimensions, reset note.
A/C Refrigerant & Oil
R-134a or R-1234yf, charge oz, PAG oil spec.
Bulb Sizes (Headlight, Tail, Fog)
Headlight, fog, tail, turn, reverse, interior.
Factory Maintenance Schedule
Service intervals by mileage, severe-duty notes, known issues.
Towing Capacity & Payload
Max tow, payload, GVWR/GCWR, hitch class by trim.
Serpentine Belt Routing & Length
Belt routing, length, rib count, OEM + aftermarket PNs.
Wheel Alignment Specifications
Camber, caster, toe ranges (front & rear), adjustability notes.
Paint Color Codes
All factory colors with paint codes, sticker location, touch-up tips.
Wiper Blade Sizes
Driver/passenger/rear blade size, attachment, OEM + cross-refs.
Spark Plug Type & Gap
Plug PN, gap, torque, interval by engine.
Transmission & Axle Gear Ratios
Trans gear ratios, axle ratios, RPO codes, tow vs MPG impact.
Key Fob Programming
DIY programming steps, FCC ID, fob PN, battery, transponder.
Same spec — other model years
2001 Sierra 2500HD
2002 Sierra 2500HD
2003 Sierra 2500HD
2004 Sierra 2500HD
2005 Sierra 2500HD
2006 Sierra 2500HD
Maintenance & repair guides
2021 GMC Sierra 2500HD Maintenance Schedule →
Available maintenance guidance; confirm the manufacturer schedule.
Repair planning references →
Plan the scope of work; detailed procedures need configuration-matched evidence.
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Values can vary by engine, trim and build date; check your VIN-specific service information. Updated 2026-06-26.