2022 Ford F-350 Super Duty Factory Maintenance Schedule

As an ASE-certified master technician, I have wrenched on countless heavy-duty trucks. The 2022 Ford F-350 Super Duty is a phenomenal workhorse, but keeping it on the road—whether you have the 6.2L gas, the 7.3L "Godzilla" gas, or the legendary 6.7L Power Stroke diesel—requires strict adherence to factory-spec maintenance. Skipping services on a heavy-duty truck doesn't just void warranties; it leads to catastrophic breakdowns when you are hauling 20,000 pounds.

Below is your definitive guide to the factory maintenance schedule for the 2022 Ford F-350 Super Duty.

Quick reference

Note: Ford uses an Intelligent Oil-Life Monitor (IOLM) that dictates oil change intervals based on driving habits. The intervals below assume a maximum 10,000-mile interval under normal driving conditions. Diesel engines have specific requirements noted below.

Severe-duty schedule

The "normal" schedule above is for trucks that commute empty on the highway. If you use your F-350 for what it was built for—towing heavy loads, idling extensively at job sites, off-roading, or operating in extreme cold or dusty climates—you must follow Ford's severe-duty schedule.

• Engine Oil & Filter: Drop the interval to every 5,000 to 7,500 miles, or every 500 engine hours (whichever comes first). Excessive idling dilutes the oil, especially on the 6.7L Power Stroke.
• Diesel Fuel Filters: In severe conditions or when using lower-quality biodiesel blends, replace fuel filters every 10,000 miles to protect the high-pressure fuel system.
• Transmission Fluid: If you tow frequently, do not wait until 150,000 miles. Replace the transmission fluid and filter every 60,000 miles.
• Transfer Case & Axle Fluids: For heavy towing or off-road use, replace differential and transfer case fluids every 60,000 miles.
• Air Filters: Dusty environments will clog an engine air filter in as little as 15,000 miles. Inspect it at every oil change.

Known issues by mileage

The 2022 generation is highly refined, but no heavy-duty truck is invincible. Here is what to watch for as the odometer climbs:

• 30,000 - 50,000 Miles (Suspension wear): Heavy front ends (especially with the diesel engine) are hard on track bar bushings, ball joints, and tie rod ends. If you experience steering wheel shimmy after hitting a bump (often dubbed "death wobble"), inspect the track bar and steering stabilizer immediately.
• 60,000 - 80,000 Miles (Emissions sensors): On 6.7L diesels, NOx sensors, EGT sensors, and the DEF heater can begin to fail or require cleaning due to soot buildup, especially if the truck sees too many short, cold trips.
• 100,000+ Miles (CP4 Fuel Pump - Diesel): The 6.7L Power Stroke utilizes a CP4 high-pressure fuel pump. While Ford improved these over the years, fuel contamination or lack of lubricity can cause pump failure, which sends metal debris through the entire fuel system. Strict fuel filter changes (every 15k) and quality fuel are your best defenses.

Estimated cost per service

Heavy-duty truck maintenance is noticeably more expensive than half-ton truck maintenance due to fluid capacities and heavy-duty parts.

• Oil & Filter Change (Gas): $80 - $120
• Oil & Filter Change (Diesel): $150 - $220 (The 6.7L takes 13 quarts of oil)
• Diesel Fuel Filters: $150 - $250
• Cabin/Engine Air Filters: $40 - $80 each
• Coolant Flush: $200 - $350 (Diesel has two separate cooling systems: primary and secondary)
• Transmission Fluid Service: $300 - $500
• Spark Plugs (Gas): $300 - $500 (Labor-intensive due to engine bay packaging)
• Differentials & Transfer Case: $250 - $400

What you can DIY vs shop

What you can DIY: If you are handy, basic maintenance on the F-350 is very doable. The truck sits high enough that you often do not even need jacks to change the oil, transfer case fluid, or differential fluid. Air filters and cabin filters require only basic hand tools. Changing the diesel fuel filters (one under the hood, one on the frame rail) is also a popular DIY job, though you must prime the fuel system afterward by cycling the ignition key several times before starting the engine.

What you should leave to the shop:

• Transmission Fluid Service: The 10R140 10-speed transmission has a complex fluid leveling procedure that requires the fluid to be at a specific temperature while checking.
• Coolant Flush: The 6.7L diesel has a dual-loop cooling system that requires a vacuum-filling tool to prevent air pockets, which can cause severe engine damage or EGR cooler failure.
• Suspension / Alignment: Diagnosing heavy-duty solid front axle vibrations and performing alignments requires specialized heavy-duty racks and alignment tools.

Stay on top of your intervals, and this truck will outlast you. When you are ready for your next service, book service on Repairius.